by: Carlos M. Garcia, MD

What is chelation? The word chelate is derived from the Greek word “chele”, which refers to the claw of a crab or lobster. Implying a firm binding between the chelating agent and the heavy metal to be sequestered and eliminated from the body. Chelation is specifically defined as the incorporation of a metal ion into a heterocyclic ring structure. (1) Think of chelation as a ham sandwich, where the EDTA is the sliced bread and the heavy metal is the ham between the slices.

There are numerous chelating agents, (A chelating agent is the molecule which binds with the heavy metal resulting in an inert (non-reactive) compound, which in the case of EDTA is eliminated by the kidneys): EDTA, ethylenediaminetetraacetic acid is used mainly for lead; there are two chelating agents for mercury: DMPS, 2,3-dimercapto-1-propanesulfonic acid and DMSA, meso-Dimercaptosuccinic acid; Iron is chelated with desferol.

Over the course of my career, I have supervised and or administered well over 83,000 IV EDTA chelation treatments for hypertension (high blood pressure), type II diabetes, diabetes induced peripheral neuropathy, kidney damage, macular degeneration and most recently dementia. This number to treatments makes me perhaps the most experienced EDTA chelating physician in the world. About 85% of my patients had a positive clinical response to intravenous EDTA infusions for these conditions as well as other medical issues.

The most frequent criticism leveled by critics of non-traditional and alternative medical therapies is that new treatments are “unproven” because randomized, double-blind controlled studies have not yet been done to prove effectiveness. Those criticisms ignore the fact that most medical procedures routinely performed in the practice of medicine are also unproven using those same criteria.

The Office of Technology Assessment, a branch of the United States Congress, with the help of an advisory board of eminent university faculty, has published a report with the conclusion that, ” . . . only 10 to 20 percent of all procedures currently used in medical practice have been shown to be efficacious by controlled trial.”  Therefore, 80% to 90% of medical procedures routinely performed are unproven. That report further points out that the research, which purports to prove effectiveness of the remaining 10% to 20% of medical procedures is largely flawed, and “many of the other procedures may not be efficacious.” The most frequent reason for not accepting the value of EDTA chelation therapy reflects a flagrant double standard. (2)

Can you explain how EDTA chelation therapy helps people with cardiovascular diseases? With each and every beat of out heart, our arterial blood system gets a pounding. You probably know of the “ideal” blood pressure of 120/80.  The 120 represents the pressure the heart generates. This pressure forces the blood against the blood vessels. Over the decades of life, this continuous abuse of our blood vessels results in damage to the intimal lining of the arterial system, our high-pressure system.  (The intima is the inner most lining of the artery, which is in contact with blood.)

The innate response of the human body to any injury is to initiate an immune response. Thus our body tries to repair the intimal damage.  During this process, which is a life long event, our body deposits fibrous tissue, platelets and other proteinaceous material within the damage area. The “glue” which appears to hold all these elements together, think of it as a patch, is calcium.  Clinically we refer to this process as vascular arterial sclerosis or vascular arterial disease. Enlargement of the plaque causes the narrowing of arterial diameter.  Narrowing of the size of the vessel produces elevated pressure and faster damage. It is a downward spiral.

EDTA intravenously, results in the binding and elimination of Calcium, the “glue”. This occurs on a molecular basis. Never once, did any of my patients ever suffer a stroke or other cardiovascular side effect. Never once, was any of their renal function ever adversely affected. On the contrary, done correctly, EDTA chelation helps renal function.

Plaque reduction results in vessel diameter enlargement. As the diameter increases, the pressures within the vessels drop. As the vessel diameter increases the blood pressure drops, which results in the decrease in blood pressure medication. The elimination of plaque results in the increase in arterial vascular elasticity.

When we are born, our blood vessels are very pliable. As stated above, with age, our arterial vessels become rigid. Rigidity results it the loss of auto-regulation. Auto-regulation is our body’s ability to dilate or constrict our blood vessels in response to increase or decrease in circulatory volume. That is: when a child drinks a lot of water, the vessels temporarily dilate to accommodate the volume, until the kidneys eliminate the excess fluid. If the child drinks insufficient water, the vessels constrict to maintain the blood pressure. This is auto-regulation; vascular arteriosclerosis prevents these functions. Intravenous EDTA chelation therapy restores this function in about 85% of those doing so.

1 – The Scientific Basis of EDTA Chelation Therapy, 2nd Ed., Halstead & Rozema, P5

2 – Assessing The Efficacy and Safety of Medical Technologies, Sept 1978 P7

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